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什么叫中药光化学疗法?效果怎么样?

发布: 2010-06-07 | 来源:www.999pifu.com | 责编: 999皮肤网 分享到新浪微博

中药光化学疗法是指用具有光敏性的中药内服或外涂,并配合长波紫外线照射的一种方法。长波紫外线(黑光)照射在白癌风中的治疗作用早有报道。紫外线能抑制表皮中琉基p增强酪氨酸酶活性,加速黑素体的生成与转移,位脱色素性病变恢复正常。长波紫外线常与映喃香豆素类药物

  中药光化学疗法是指用具有光敏性的中药内服或外涂,并配合长波紫外线照射的一种方法。长波紫外线(黑光)照射在白癌风中的治疗作用早有报道。紫外线能抑制表皮中琉基p增强酪氨酸酶活性,加速黑素体的生成与转移,位脱色素性病变恢复正常。长波紫外线常与映喃香豆素类药物合用以增加疗效。
  国外用三甲基补骨脂素加黑光照射治疗白癜风取得较好疗效。国内曾用8—甲氧基补骨脂素(8—MOP)配合黑光照射治疗银屑病,同时也用于白短风的治疗,取得一定的疗效(详见第60题的解答)。近年来研究发现有些中草药亦含有映喃香豆素类物质,将这些中草药加工后内服或外涂白斑,继之加照黑光或晒太阳,以引发光敏反应达到治疗白疯风的目的。其中以补骨脂最常用。中药补骨脂含补骨脂素和异构补骨脂素等物质,能提高皮肤对紫外线的敏感性而发挥治疗白痈风的作用。有较多报道用补骨脂单独或与其它药物配合制成片剂、针剂或外涂药,配合日晒治疗白痴风取得疗效。如有人用30%补骨脂可(朴骨脂300克浸泡于70%乙醇700毫升中,密封7天后,过滤去渣,取液外用)治疗7例白放风,结果5例收到满意疗效。有人用法白素片(中药补骨脂的提取物,含补骨脂素与异构补骨脂素的混合物,每片5毫克,每日3—20片,分3次口服)内服及外涂1%祛白素药水治疗27例白癌风,结果痊愈2例、显效9例、有效14例、无效2例。总有效率92.60%。也有人认为单涂补骨脂配治疗白短风有效者罕见,而改用制斑素(含补骨脂素)针剂,每次肌肉注射4毫升(含补骨脂生药5克),加外涂补骨脂配治疗137例白魔风,结果痊愈5例、显效32例、好转56例、无效44例。总有效率67.90%。另有人报道用制斑素(含补骨脂索)肌肉注射结合外涂治疗207例白瘫风,结果186例有效,有效率达89.9%,其中显效率达39.7%。包有人在辩证用药处方中加补骨脂以提高疗效。
  从上述介绍可以看出补骨脂治疗白癜风的疗效差异颇大,推测其原因有:1.补骨脂的粗制品与提取较纯的精品中补骨脂素的含量不同,精制品中补骨脂素含量高,疗效亦较好;2.个体对药物的治疗反应有差异;3.白斑的分布部位与白斑的类型影响疗效,如面部等暴露部位的白斑较被覆部位的白斑疗效好;局限型与散发型白斑疗效较好,而偏侧型与胶端型则较差。4.很重要的一点是这类药物需要借助于紫外线的照射才能发挥药效,因此在治疗期间能主动配合日晒者疗效就比较好,反之,治疗效果就较差

Chinese medicine refers to photochemical treatment of Chinese Herbs with photosensitivity or applied externally, and with a method of ultraviolet irradiation. Long-wave ultraviolet (black light) irradiation in the white wind in the treatment of cancer has long been reported. UV can inhibit the epidermal thiol p increase in tyrosinase activity, accelerate the formation of melanosomes and transfer, bit marking primality lesions returned to normal. Chang and Ying-Nan UVA coumarin combined to increase the efficacy of drugs.
Foreign use of trimethyl psoralen plus black light irradiation treatment of vitiligo get better effect. China has used 8 - methoxypsoralen (8-MOP) with black light irradiation treatment of psoriasis, but also for the treatment of white short wind, get a certain effect (see answer to question 60). Recent studies have found that some herbs also contain substances Ying Nan coumarin, after processing these herbs taken orally or applied externally white, followed by Canada according to black light or the sun to cause photosensitive reactions to achieve the purpose of treating white crazy wind. Among the most commonly used psoralen. Chinese medicine containing psoralen psoralen psoralen and other heterogeneous materials, can increase skin sensitivity to UV play a role in the treatment of white carbuncle wind. Reported more use of psoralen alone or with other drugs made with the tablet, injection or external applicator, the treatment with the sun and the wind made an idiot effect. If people use 30% of the psoralen can (300 grams of fat Park bone immersed in 70% ethanol 700 ml, the seal 7 days, filtered to the residue, fluid obtained external) of 7 cases of white hinted that satisfactory efficacy results of 5 cases . Some use of interleukin-chip (Chinese Psoraleae extract containing psoralens and heterogeneous mixture of psoralen, 5 mg per tablet, 3-20 tablets daily, divided into 3 sub-Oral) Oral and exterior coating Removing interleukin 1% of white cancer medicine treatment of 27 patients with the wind, the results recovered, 2 cases were 9 cases, 14 cases of effective and ineffective in 2 cases. The total effective rate 92.60%. Also suggested that a single painted white short psoralen with the wind force on treatment of rare, but switch to spot prime the system (including psoralen) injection, intramuscular injection of 4 ml each (containing 5 g crude drug psoralen), plus external Tu psoralen treatment of 137 cases of white magic with the wind, the results recovered in 5 cases, 32 cases markedly improved and 56 cases, 44 cases ineffective. The total effective rate 67.90%. Others reported that plaque with a system of factors (including psoralen Cable) External Application of intramuscular treatment of 207 cases of white combined with paralysis wind, the results of 186 cases, and the effective rate was 89.9%, which markedly effective rate was 39.7%. Package was in the dialectical psoralen plus prescription drugs to improve efficacy. (责任编辑:999皮肤网)

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